Injectable Fillers

Dermal fillers in Singapore:
choosing the material before the product

Medically reviewed by Dr Sin Yong · Last reviewed · 12 min read

Published 7 October 2026 · Reviewed by Dr Sin Yong

Three clear glass ampoules with pale blue liquid on a wet white marble surface, an illustrative image

Dermal fillers in Singapore are injectable gels registered with the Health Sciences Authority and placed by a doctor. They fall into four materials: hyaluronic acid, which occupies space and can be dissolved; calcium hydroxylapatite and polycaprolactone, which give early volume and then support collagen but cannot be dissolved; and poly-L-lactic acid, which works through collagen alone. A filler adds volume; it does not lift or tighten. Material, area and tissue plane are chosen after examination.

Also called: hyaluronic acid filler, 玻尿酸填充, ヒアルロン酸注入

People also search for
Filler gone wrongWill I look fake?Occlusion warning signsDissolving fillerToxin vs fillersUnder-eye filler costAftercareFees: what decides them
Illustrative close view of three glass ampoules and water droplets on white marble
Illustrative image. The material, the area and the tissue plane are decided at examination, not by brand.
Key facts
What a filler does
Occupies space to restore volume or projection; it does not lift or tighten
Hyaluronic acid
Cross-linked gel and the usual first choice, because hyaluronidase can dissolve it
CaHA and PCL
Radiesse and Ellansé: the gel gives early volume, then microspheres support collagen; neither can be dissolved
PLLA
Sculptra: a biostimulator that works through collagen over time; it cannot be dissolved
Regulation
Fillers are HSA-registered medical devices, injected by a registered doctor after assessment
Highest-risk zones
Nose, glabella, forehead and tear trough, where arteries connect with the circulation of the eye
Decided by
Examination of the whole face; fees are set out in writing at consultation
Filler injection planesSkin cross-section from epidermis to bone marking where hyaluronic acid fillers and biostimulators are commonly placed, with an artery drawn through the planes to mark the vascular caution.Filler planes: where HA and biostimulators are commonly placedEpidermisSuperficial dermisDeep dermisSubcutaneous fatSupraperiosteal planeBonethin HA for fine linesHA in the deep dermissofter HA · biostimulatorsstructural, on bonearteryHA filler: dermis, fat or on bone, depending on the indicationBiostimulators: deep subcutaneous or supraperiosteal, not the superficial dermisArteries run through these planes: anatomy, aspiration, slow low-volume injection and cannulas reduce risk
Where HA fillers and biostimulators are commonly placed, from superficial dermis to bone, with the arterial anatomy that drives the vascular caution.

What are the four types of dermal filler?

Dermal fillers in Singapore come in four materials, and the material decides what can be undone. Hyaluronic acid (HA) is a sugar already present in the skin; in a filler it is cross-linked into a gel that holds its shape. Calcium hydroxylapatite (CaHA, as in Radiesse) and polycaprolactone (PCL, as in Ellansé) are microspheres suspended in a carrier gel. Poly-L-lactic acid (PLLA, as in Sculptra) is a biodegradable polymer that is a biostimulator rather than a filler in the strict sense.

With hyaluronic acid the volume is the product itself, so what you see on the day is largely what is there. With CaHA and PCL the carrier gives early volume and is absorbed, and the microspheres remain for a time as a scaffold on which the body lays down its own collagen. With PLLA there is no lasting volume from the product on the day; the change comes from the collagen it prompts.

Hyaluronidase dissolves hyaluronic acid and nothing else. That single fact shapes where each material is used, how much is placed, and how cautiously a first treatment is planned.

What can a dermal filler not do?

A dermal filler cannot lift tissue, tighten loose skin or act on a muscle. It is not a skin booster, which acts within the skin on hydration and quality without projecting or contouring, and it is not botulinum toxin, which relaxes muscle. Which of the three fits depends on which tissue is responsible for what you see.

The commonest mistake is to ask a filler to do the work of a lift. Facial ageing is volume loss, laxity and declining skin quality arriving together, and a filler acts only on the first. Given to a face whose main change is descent, it produces a heavier lower face with the same sag. Filler is declined where the expectation is something it cannot do, such as lifting a jowl, tightening skin or making a nose smaller.

Because a filler restores structure, the first question is always what is missing: structure before volume, bone before soft tissue, and a plan for the whole face rather than a count of syringes. Over-filling is avoided by asking what is missing before asking what to add, and by checking what earlier treatment is already present.

“A filler adds volume. It does not lift, and it does not tighten. Asking it to do either is how faces end up over-filled.”

Dr Sin YongOn what a filler cannot do

Which material goes in which area?

Which material goes where depends on what the area has to do: project against bone, soften a hollow, or move with expression. The cheek, chin and jawline need support on bone, so a firmer hyaluronic acid or, where reversibility is not the priority, CaHA or PCL is placed deep. The cheek filler and chin filler pages set out how each area is planned.

The nose is a special case. Here the nose bridge is usually treated with CaHA or PCL for the support they give, with hyaluronic acid where a dissolvable option is preferred, and filler can straighten or raise a bridge but cannot make a nose smaller. The nose filler page covers the limits and the vascular risk.

Lips and tear troughs take soft hyaluronic acid in small amounts, because these areas move constantly, sit close to the surface and benefit from a material that can be dissolved. Diffuse volume loss across the mid-face and temples is often better suited to a collagen biostimulator such as Sculptra or Ellansé than to filler placed point by point; the Radiesse, Ellansé and Sculptra pages describe each one.

Dermal filler materials compared
MaterialWhat it isHow it persists in tissueCan it be dissolved?Typical areasWho should avoid it
Hyaluronic acidCross-linked gel that occupies spaceBroken down gradually by the body; can remain after the visible effect fadesYes, with hyaluronidaseCheeks, chin, jawline, temples, lips, tear trough, handsAllergy to a component; infection near the site
Calcium hydroxylapatite (Radiesse)Microspheres in a carrier gelCarrier absorbed first; microspheres break down slowly while collagen formsNoChin, jawline, cheek, nose bridge, handsNot for lips, tear troughs or glabella; allergy; bleeding disorder
Polycaprolactone (Ellansé)Microspheres in a carrier gelCarrier absorbed first; microspheres are metabolised slowlyNoChin, jawline, temples, backs of handsAutoimmune disease; severe allergy; not for lips or tear troughs
Poly-L-lactic acid (Sculptra)Biodegradable polymer that prompts collagenWorks through the collagen it stimulates, not the product itselfNoDiffuse volume loss in mid-face, temples, lower faceNot for lips, tear troughs or fine lines; keloid tendency

Who suits fillers, and who should wait?

Filler suits a change that is genuinely volumetric in a face whose skin and ligaments still give support: deflated cheeks or temples, a hollow tear trough, or shapes that were never age-related, such as a short chin, a low nasal bridge or thin lips. Someone new to injectables is often better starting with a reversible hyaluronic acid filler than with a material that cannot be dissolved. Where the main change is heavy, redundant skin, filler is not the first answer: laxity is assessed for lifting, and marked excess is referred to a plastic surgery specialist.

Treatment is deferred in pregnancy and breastfeeding, and where there is an active infection, a cold sore or inflamed skin near the site. A known allergy to a component or to lidocaine, a bleeding tendency or blood-thinning medicine, autoimmune conditions and a keloid tendency are discussed first. Earlier non-resorbable fillers, such as silicone, must be declared, because layering new product over them raises the risk of nodules, and previous filler of any type is scanned with ultrasound where the history is unclear.

What are the risks, and when should you call?

The serious risk of any filler is vascular occlusion, in which product enters or presses on an artery and the tissue it supplies loses its blood flow. Warning signs are skin that blanches white or turns dusky, purple or net-like, and pain out of proportion to the injection. These need same-day assessment. Any change in vision after filler is an emergency: go to the nearest hospital emergency department or call 995 rather than travelling to a clinic first.

Occlusion is rare, and the highest-risk zones are the nose, the glabella, the forehead and the tear trough. For hyaluronic acid it is treated with urgent, high-dose hyaluronidase, which is kept in the room wherever hyaluronic acid is injected. CaHA, PCL and PLLA have no dissolving option, which is why they are placed conservatively and why the nose, where Dr Sin Yong usually works with CaHA or PCL, is planned with particular care.

Other risks are bruising and swelling, lumps, product that migrates, a bluish tint where hyaluronic acid sits too close to the surface, and inflammatory nodules that can appear months or years later. Filler that looks heavy, has moved or feels lumpy is assessed under filler correction, and the signs that need urgent attention are set out under complication care.

What happens, step by step?

The first visit is an assessment, not a treatment. Dr Sin Yong takes the history, including any earlier filler and where it was given, examines the whole face at rest and in movement, and may photograph it for your medical record. Ultrasound can show where existing product sits. You then receive a written plan naming the areas, the material, the plane and the fee, and you can take it away; you are not expected to decide on the day.

On treatment day the skin is cleaned and a topical anaesthetic is applied, and most hyaluronic acid fillers also contain lidocaine. Product is placed with a needle or a blunt cannula, chosen area by area, in small amounts that are checked against the other side before more is added. Written aftercare explains what is expected and which signs to report, and the result is reviewed once swelling has settled.

Swelling, tenderness and some bruising at the entry points are expected, and lips and tear troughs swell more than bony areas. Temporary asymmetry while swelling settles at different rates is common and is not a reason to add more product.

What determines the fee?

The fee depends on the areas treated and how many, what the examination finds in each, the material chosen and the quantity the anatomy calls for, whether filler is used alone or with botulinum toxin or a biostimulator, and whether the plan is staged across more than one visit. Correcting earlier filler is costed separately from new treatment.

Singapore's rules for medical advertising prevent fees from being published, and a quote given before examination would be for a plan that does not yet exist. A written, itemised quote is given after the consultation, and how fees are quoted sets out what it contains.

Go deeper on Dermal Fillers

Frequently Asked Questions

The four materials are hyaluronic acid, calcium hydroxylapatite (Radiesse), polycaprolactone (Ellansé) and poly-L-lactic acid (Sculptra). Hyaluronic acid occupies space and can be dissolved; the other three stimulate collagen and cannot. The choice depends on the area, the tissue plane and whether reversibility matters.

Only hyaluronic acid filler can be dissolved, with an enzyme called hyaluronidase. Radiesse, Ellansé and Sculptra do not respond to it and are managed case by case if a problem arises. This is why hyaluronic acid is the usual first choice, and the only choice in the tear trough.

Skin that turns white, dusky, purple or net-like, and pain that is severe or getting worse, need same-day assessment. Any change in vision is an emergency and means the nearest hospital emergency department or 995. Ordinary swelling and bruising settle; these signs do not.

The fee depends on the areas treated, what the examination finds, the material and quantity, whether filler is combined with botulinum toxin or a biostimulator, and whether the plan is staged. Singapore's rules prevent prices being advertised, so a written quote is given after the consultation.

They can be worth it where volume is genuinely missing, such as a deflated cheek, a short chin or a hollow temple, in a face with supportive skin. They are not worth it as a substitute for a lift or for tightening loose skin. The examination decides which problem you have.

No duration can be promised. It depends on the material, how it is cross-linked, where it is placed and your own metabolism. Hyaluronic acid can remain in tissue after its visible effect has faded, so existing product is assessed, with ultrasound if needed, before anything is added.

Swelling, bruising, lumps, migration and a bluish tint under thin skin can occur, and inflammatory nodules can appear late. Rarely, a blocked blood vessel is an emergency. Only hyaluronic acid can be dissolved, and over-filling accumulates if product is added repeatedly without checking what is already there.

Filler is deferred during pregnancy and breastfeeding, because its safety in these groups has not been established. It is also deferred with an active infection or cold sore near the site. Autoimmune and inflammatory conditions are assessed individually, and previous non-resorbable filler must be declared.

References

Dermal Fillers (Soft Tissue Fillers). U.S. Food and Drug Administration. source

Medical devices: regulatory overview. Health Sciences Authority, Singapore. source

Update on Avoiding and Treating Blindness From Fillers: A Recent Review of the World Literature. Aesthetic Surgery Journal (Beleznay K, Carruthers JDA, Humphrey S et al.), 2019. source

New High Dose Pulsed Hyaluronidase Protocol for Hyaluronic Acid Filler Vascular Adverse Events. Aesthetic Surgery Journal (DeLorenzi C), 2017. source

Explore Further
Related reading

Speak With Dr Sin Yong

Consultations by appointment at Orchard Road, Singapore.

  1. 1WhatsApp a short note on your concern
  2. 2Consultation and assessment with Dr Sin Yong
  3. 3Options explained, including no treatment

Replies within clinic hours: Mon–Fri 10am–8pm, Sat 11am–3pm · How consultations work · Prefer not to use WhatsApp? · Treatment finder

WhatsApp +65 8023 7170 →
Follow Dr Sin Yong
InstagramTikTokYouTubeThreadsXLinkedInFacebook